Publications
Flow-cytometric detection of minimal residual disease in adult acute lymphoblastic leukemia
M. Krampera, O. Perbellini, A. Maggioni, F. Scognamiglio, G. Todeschini, G. Pizzolo.
Haematologica. 2001;86(3):322–323
Bone marrow mesenchymal stem cells inhibit the response of naïve and memory antigen-specific T cells to their cognate peptide
M. Krampera, S. Glennie, R. Laylor, J. Dyson, D. Scott, E. Simpson, F. Dazzi.
Blood. 2003;101(9):3722–3729.
Thymic epithelial cells promote survival of human T-cell acute lymphoblastic leukemia blasts: the role of interleukin-7
M.T. Scupoli, F. Vinante, M. Krampera, C. Vincenzi, G. Nadali, F. Zampieri, M.A. Ritter, E. Eeren, F. Santini, G. Pizzolo.
Haematologica. 2003;88(11):1229–1237.
Outcome prediction by immunophenotypic minimal residual disease detection in adult T cell acute lymphoblastic leukemia
M. Krampera, A. Vitale, C. Vincenzi, O. Perbellini, A. Guarini, L. Annino, G. Todeschini, A. Camera, F. Fabbiano, G. Fioritoni, F. Nobile, R. Szydlo, F. Mandellli, R. Foà, G. Pizzolo.
Br J Haematol. 2003;120(1):74–79.
Induction of unresponsiveness limits tumor protection by adoptively transferred MDM2-specific cytotoxic T lymphocytes
G.M. Bendle, A. Holler, L.K. Pang, S. Hsu, M. Krampera, E. Simpson, H.J. Stauss.
Cancer Res. 2004;64(21):8052–8056.
HB-EGF/HER-1 signalling in bone marrow mesenchymal stem cells: inducing cell expansion and reversibly preventing multi-lineage differentiation
M. Krampera, A. Pasini, A. Rigo, M.T. Scupoli, C. Tecchio, G. Malpeli, A. Scarpa, F. Dazzi, G. Pizzolo, F. Vinante.
Blood. 2005;106(1):59–66.
Role for interferon-gamma in the immunomodulatory activity of human bone marrow mesenchymal stem cells
M. Krampera, L. Cosmi, R. Angeli, A. Pasini, F. Liotta, A. Andreini, V. Santarlasci, B. Mazzinghi, G. Pizzolo, F. Vinante, P. Romagnani, E. Maggi, S. Romagnani, F. Annunziato.
Stem Cells. 2006;24(2):386–398.
Adult T-cell acute lymphoblastic leucemia: biologic profile at presentation and correlation with response to induction treatment in patients enrolled in the GIMEMA LAL 0496 protocol
A. Vitale, A. Guarini, C. Ariola, M. Mancini, C. Mecucci, A. Cuneo, F. Pane, G. Saglio, G. Cimino, A. Tafuri, G. Meloni, F. Fabbiano, A. Recchia, M.G. Kropp, M. Krampera, N. Cascavilla, F. Ferrara, A. Romano, P. Mazza, C. Fozza, F. Paoloni, M. Vignetti, R. Foà.
Blood. 2006;107(2):473–479.
Regenerative and immunomodulatory potential of mesenchymal stem cells
M. Krampera, A. Pasini, G. Pizzolo, L. Cosmi, S. Romagnani, F. Annunziato.
Curr Opin Pharmacol. 2006;6(4):435–441.
Mesenchymal stem cells for bone, cartilage, tendon and skeletal muscle repair
M. Krampera, G. Pizzolo, G. Aprili, M. Franchini.
Bone. 2006;39(4):678–683.
Le cellule staminali mesenchimali
M. Krampera, G. Pizzolo.
Seminari di Ematologia Oncologica 3(2):131-153, 2006
Methodological approach to minimal residual disease detection by flow cytometry in adult B-lineage acute lymphoblastic leukemia
M. Krampera, O. Perbellini, C. Vincenzi, F. Zampieri, A. Pasini, M.T. Scupoli, A. Guarini, S. De Propris, E. Coustan-Smith, A. Vitale, D. Campana, R. Foà, G. Pizzolo.
Haematologica. 2006;91(8):1109–1112.
Clinical treatment of radiotherapy tissue damages by lipoaspirates transplant: a healing process mediated by adipose-derived adult stem cells (ASCs)
G. Rigotti, A. Marchi, M. Galiè, G. Baroni, D. Benati, M. Krampera, A. Pasini, A. Sbarbati.
Plast Reconstr Surg. 2007;119(5):1409–1424.
Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus
M. Krampera, S. Marconi, A. Pasini, M. Galiè, F. Mosna, M. Tinelli, L. Lovato, E. Anghileri, A. Andreini, G. Pizzolo, A. Sbarbati, B. Bonetti.
Bone. 2007;40(2):382–390.
Interleukin-7 requirement for survival of T-cell acute lymphoblastic leukemia and human thymocytes on bone marrow stroma
M.T. Scupoli, O. Perbellini, M. Krampera, F. Vinante, F. Cioffi, G. Pizzolo.
Haematologica. 2007;92(2):264–266.
Immune regulation by mesenchymal stem cells derived from adult spleen and thymus
M. Krampera, S. Sartoris, L. Cosmi, A. Pasini, R. Angeli, F. Liotta, M. Tinelli, A. Andreini, F. Mosna, E. Rebellato, M.G. Testi, V. Santarlasci, G. Pizzolo, G. Tridente, E. Maggi, S. Romagnani, F. Annunziato.
Stem Cells Dev. 2007;16(5):797–810.
Mesenchymal stem cells: from biology to clinical use
M. Krampera, M. Franchini, G. Pizzolo, G. Aprili.
Blood Transfus. 2007;5(3):120–129.
Immune modulation of mesenchymal stem cells
F. Bifari, V. Lisi, E. Mimiola, A. Pasini, M. Krampera.
Transfus Med Hemother. 2008;35(3):194–204.
Stem molecular signature of adipose-derived stromal cells
D. Peroni, I. Scambi, A. Pasini, V. Lisi, F. Bifari, M. Krampera, G. Rigotti, A. Sbarbati, M. Galiè.
Exp Cell Res. 2008;314(3):603–615.
Neuronal differentiation potential of human mesenchymal stem cells
E. Anghileri, S. Marconi, A. Pignatelli, P. Cifelli, M. Galié, A. Sbarbati, M. Krampera, O. Belluzzi, B. Bonetti.
Stem Cells Dev. 2008;17(5):909–916.
Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favors the early tumor growth in syngeneic mice
M. Galiè, G. Konstantinidou, D. Peroni, I. Scambi, C. Marchini, V. Lisi, M. Krampera, P. Magnani, F. Merigo, M. Montani, F. Boschi, P. Marzola, R. Orrù, P. Farace, A. Sbarbati, A. Amici.
Oncogene. 2008;27(18):2542–2551.
TLR3 and TLR4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signalling
F. Liotta, R. Angeli, L. Cosmi, L. Filì, C. Manuelli, F. Frosali, B. Mazzinghi, L. Maggi, A. Pasini, V. Lisi, V. Santarlasci, L. Consoloni, P. Romagnani, P. Parronchi, M. Krampera, E. Maggi, S. Romagnani, F. Annunziato.
Stem Cells. 2008;26(1):279–289.
Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-kB and JNK/AP-1 pathways
M.T. Scupoli, M. Donadelli, F. Cioffi, M. Rossi, O. Perbellini, G. Malpeli, S. Corbioli, F. Vinante, M. Krampera, M. Palmieri, A. Scarpa, C. Ariola, R. Foà, G. Pizzolo.
Haematologica. 2008;93(4):524–532.
Novel stem/progenitor cells with neuronal differentiation potential reside in the leptomeningeal niche
F. Bifari, I. Decimo, C. Chiamulera, E. Bersan, G. Malpeli, J. Johanson, V. Lisi, B. Bonetti, G. Fumagalli, G. Pizzolo, M. Krampera.
J Cell Mol Med. 2009;13(9B):3195–3208.
DHFR 19-bp insertion/deletion polymorphism and MTHFR C677T in adult acute lymphoblastic leukemia: is the risk reduction due to intracellular folate unbalancing?
D. Gemmati, M. De Mattei, L. Catozzi, M. Della Porta, M.L. Serino, C. Ambrosio, A. Cuneo, S. Friso, M. Krampera, E. Orioli, G. Zeri, A. Ongaro.
Am J Hematol. 2009;84(8):526–529.
Adipose-derived mesenchymal stem cells ameliorate chronic EAE by immunosuppression and neuroregeneration
G. Constantin, S. Marconi, B. Rossi, S. Angiari, A. Pasini, M. Galiè, B. Gini, F. Bifari, A. Sbarbati, M. Krampera, B. Bonetti.
Stem Cells. 2009;27(10):2624–2635.
Mesenchymal stem cells for clinical application
L. Sensebé, M. Krampera, H. Schrezenmeier, P. Bourin, R. Giordano.
Vox Sang. 2010;98(2):93–107
The puzzling uniqueness of the heterotrimeric G15 protein and its potential beyond hematopoiesis
F. Giannone, G. Malpeli, V. Lisi., S. Grasso, P. Shukla, D. Ramarli, V. Monsurrò, S. Sartoris, M. Krampera, E. Amato, G. Tridente, M. Colombatti, M. Parenti, G. Innamorati.
J Mol Endocrinol. 2010;44(5):259–269
IFN-alpha- Mediated Upmodulation of MHC Class I Expression Activates Tumor-Specific Immune Response in a Mouse Model of Prostate Cancer
M. Martini, M.G. Testi, M. Pasetto, M.C. Picchio, G. Innamorati, M. Mazzocco, S. Ugel, S. Cingarlini, V. Bronte, P. Zanovello, M. Krampera, F. Mosna, T. Cestari, A.P. Riviera, N. Brutti, O. Barbieri, L. Matera, G. Tridente, M. Colombatti, S. Sartoris.
Vaccine. 2010;28(20):3548–3557.
Immunological properties of embryonic and adult stem cells
F. Bifari, L. Pacelli, M. Krampera.
World J Stem Cells. 2010;2(3):50–60.
Human bone-marrow and adipose tissue mesenchymal stem cells:a user’s guide
F. Mosna, L. Sensebé, M. Krampera.
Stem Cells Dev. 2010;19(10):1449–1470.
Cell therapy for cardiac regeneration after myocardial infarct: which cell is the best?
F. Mosna, F. Annunziato, G. Pizzolo, M. Krampera.
Cardiovasc Hematol Agents Med Chem. 2010;8(4):227–243.
Efficacy assessment of interferon-alpha-engineered mesenchymal stromal cells in a mouse plasmacytoma model
S. Sartoris, M. Mazzocco, M. Tinelli, M. Martini, F. Mosna, V. Lisi, S. Indraccolo, L. Moserle, T. Cestari, A.P. Riviera, F. Bifari, G. Tridente, G. Pizzolo, M. Krampera.
Stem Cells Dev. 2011;20(4):709–719.
Mesenchymal stem cells and autoimmune diseases
F. Dazzi, M. Krampera.
Best Pract Res Clin Haematol. 2011;24(1):49–57
Mesenchymal stromal cells: more than inhibitory cells
M. Krampera.
Leukemia. 2011;25(4):565–566.
TLR-3-activated human mesenchymal stromal cells significantly prolong the survival and function of neutrophils
M.A. Cassatella, F. Mosna, A. Micheletti, V. Lisi, N. Tarmassia, C. Cont, F. Calzetti, M. Pellettier, G. Pizzolo, M. Krampera.
Stem Cells. 2011;29(6):1001–1011.
Mesenchymal stromal cell ‘licensing’: a multistep process
M. Krampera.
Leukemia. 2011;25(9):1408–1414.
Cellule staminali e rigenerazione cardiaca
F. Mosna, G. Pizzolo, M. Krampera.
Seminari di Ematologia Oncologica 2, 2011.
Notch-3 and Notch-4 signaling rescue from apoptosis human B-lineage acute lymphoblastic leukemia cells in contact with human bone marrow-derived mesenchymal stromal cells
A.H. Nwabo Kamdje, F. Mosna, F. Bifari, V. Lisi, O.Perbellini, M.T. Scupoli, G. Pizzolo, M. Krampera.
Blood. 2011;118(2):380–389.
Neural stem cell niches in health and diseases
I. Decimo , F. Bifari, M. Krampera, G. Fumagalli.
Curr Pharm Des. 2012;18(13):1755–1783.
Mesenchymal stem cell isolation and expansion methodology
M. Ricciardi, L. Pacelli, G. Bassi, F. Bifari, F. Mosna, M. Krampera.
Stem Cells And Cancer Stem Cells: Therapeutic Applications in Disease and Injury, Springer Editor, 2012
Nestin- and DCX-positive cells reside in adult spinal cord meninges and participate to injury-induced parenchymal reaction
I. Decimo, F. Bifari, F.J. Rodriguez, S. Dolci, V. Lavarini, S. Pretto, S. Vasquez, G. Malpeli, M. Sciancalepore, A. Montalbano, M. Krampera, G. Fumagalli.
Stem Cells. 2011;29(12):2062–2076.
Notch signaling in acute lymphoblastic leukemia: any role for stromal microenvironment?
A.H. Nwabo Kamdje, M. Krampera.
Blood. 2011;118(25):6506–6514.
Adipose-derived stromal cells (ASCs)
G. Bassi, L. Pacelli, R. Carusone, J. Zanoncello, M. Krampera.
Transfus Apher Sci. 2012;47(2):193–198.
Limited acquisition of chromosomal aberrations in human adult mesenchymal stromal cells
L. Sensebé, K. Tarte, J. Galipeau, M. Krampera, I. Martin, D.G. Phinney, Y. Shi, on behalf of MSC Committee of International Society for Cellular Therapy (ISCT).
Cell Stem Cell. 2012;10(1):9–11.
Comparison of epithelial differentiation and immune regulatory properties of mesenchymal stromal cells derived from human lung and bone marrow
M. Ricciardi, G. Malpeli, F. Bifari, G. Bassi, L. Pacelli, A.H. Nwabo Kamdje, M. Chilosi, M. Krampera.
PLoS One. 2012;7(5):e35639.
Meninges: from protective membrane to stem cell niche
I. Decimo, G. Fumagalli, V. Berton, M. Krampera, F. Bifari.
Am J Stem Cells. 2012;1(2):92–105.
Role of stromal cell-mediated Notch signaling in B-CLL cell survival and resistance to chemotherapy
A.H. Nwabo Kamdje, G. Bassi, L. Pacelli, G. Malpeli, E. Amati, I. Nichele, G. Pizzolo, M. Krampera.
Blood Cancer J. 2012;2(5):e73.
Normal hematopoiesis and hematologic malignancies: role of canonical Wnt signaling pathway and stromal microenviroment
P.F. Seke Etet, L. Vecchio, P. Bogne Kamga, E.N. Nukenine, M. Krampera, A.H. Nwabo Kamdje.
Biochim Biophys Acta. 2013;1835(1):1–10.
Quantitative Fluorescence In situ Hybridization on paraffin embedded tissue
M. Ricciardi, M. Krampera, M. Chilosi.
Methods Mol Biol. 2013;976:167–173.
Immunological characterization of Multipotent Mesenchymal Stromal Cells. The International Society for Cellular Therapy working proposal
M. Krampera, J. Galipeau, Y. Shi, F. Dazzi, K. Le Blanc, K. Tarte,L. Sensebé, on behalf of the MSC Committee of the International Society for Cellular Therapy (ISCT).
Cytotherapy 2013;15(9):1054-1061.
VR09: an EBV-positive lumphoblastoid cell line with in vivo characteristics of diffuse large B cell lymphoma of activated B-cell type
I. Nichele, A. Zamò, A. Bertolaso, F. Bifari, M. Tinelli, M. Franchini, R. Stradoni, F. Aprili, G. Pizzolo, M. Krampera.
PLoS One. 2012;7(12):e52811
The TNF-family cytokine TL1A inhibits the proliferation of human activated B cells
C. Cavallini, O. Lovato, A. Bertolaso, L. Pacelli, E. Zoratti, E. Zanolin, M. Krampera, A. Zamò, C. Tecchio, M.A. Cassatella, G. Pizzolo, M.T. Scupoli.
PLoS One. 2013;8(4):e60136
Clinical-grade mesenchymal stromal cells produced under various good manufacturing practice processes differ in their immunomodulatory properties: standardization of immune quality controls
C. Menard, L. Pacelli, G. Bassi, J. Dulong, F. Bifari, I. Bezier, J. Zanoncello, M. Ricciardi, M. Latour, P. Bourin, H. Schrezenmeier, L. Sensebé, K. Tarté, M. Krampera.
Stem Cells Dev. 2013;22(12):1789–1801.
Importance of epigenetic changes in cancer etiology, pathogenesis, clinical profiling, and treatment: what can be learned from hematologic malignancies?
L. Vecchio, P.F. Seke Etet, M.J. Kipanyula, M. Krampera, A.H. Nwabo Kamdje.
Biochim Biophys Acta. 2013;1836(1):90–104.
MSCs: science and trials
D.G. Phinney, J. Galipeau, M. Krampera, I. Martin, Y. Shi, L. Sensebé
Nat Med. 2013;19(7):812.
Comparative study of immune regulatory properties of stem cells derived from different tissues
M. Di Trapani, G. Bassi, M. Ricciardi, E. Fontana, F. Bifari, L. Pacelli, L. Giacomello, M. Pozzobon, F. Feron, P. De Coppi, P. Anversa, G. Fumagalli, I. Decimo, C. Menard, K. Tarte, M. Krampera.
Stem Cells Dev. 2013;22(22):2990–3002.
Mesenchymal stem cell biodistibution,migration, and homing in vivo
W. Zhao, D.G. Phinney, D. Bonnet, M. Dominici, M. Krampera.
Stem Cells Int. 2014;2014:292109.
Signaling pathway in breast cancer: therapeutic targeting of the microenvironment
A.H. Nwabo Kamdje, P.F. Seke Etet, L. Vecchio, J.M. Muller, M. Krampera, K.E. Lukong.
Cell Signal. 2014;26(12):2843–2856.
New targeted therapies for breast cancer: a focus on tumor microenvironmental signals and chemoresistant breast cancers
A.H. Nwabo Kamdje, P.F. Seke Etet, L. Vecchio, R. Simo Tagne, J Mbo Amvene, JM Muller, M. Krampera, K.E. Lukong.
World J Clin Cases. 2014;2(12):769–786.
Effects of a ceramic biomaterial on immune modulatory properties and differentiation potential of human mesenchymal stromal cells of different origin
G. Bassi, F. Guilloton, C. Menard, M. Di Trapani, F. Deschaseaux, L. Sensebé, H. Schrezenmeier, R. Giordano, P. Bourin, M. Dominici, K. Tarte, M. Krampera.
Tissue Eng Part A. 2015;21(3-4):767–781.
Immunophenotypic analysis in patients suffering from Shwachmann-Bodian-Diamond Syndrome
A. Mercuri, E. Cannata, O. Perbellini, C. Cugno, R. Balter, A. Zaccaron, G. Tridello, G. Pizzolo, M. De Bortoli, M. Krampera, M. Cipolli, S. Cesaro
Eur J Haematol. 2015;95(4):308–315.
The challenge of defining mesenchymal stromal cell potency assays and their potential use as release criteria
J. Galipeau, M. Krampera.
Cytotherapy 2015;17(2):125-127.
Epithelial-to-Mesenchymal Transition (EMT) induced by inflammatory priming elicits mesenchymal stromal cell-like immune modulatory properties in cancer cells
M. Ricciardi, M. Zanotto, G. Malpeli, G. Bassi, O. Perbellini, M. Chilosi, F. Bifari, M. Krampera.
Br J Cancer. 2015;112(6):1067–1075.
Injection Moulded polymeric micropatterns for bone regeneration study
E. Zanchetta, E. Guidi, G. Della Giustina, M. Sorgato, M. Krampera, G. Bassi, R. Di Liddo, G. Lucchetta, M.T. Conconi, G. Brusatin.
ACS Appl Mater Interfaces. 2015;7(13):7273–7281.
Imatinib-treated chronic myeloid leukemia patients with discordant response between cytogenetics and molecular tests at 3 and 6 month time-points have a reduced probability of subsequent optimal response
M. Bonifacio, G. Binotto, E. Maino, E. Calistri, L. Marin, L. Scaffidi, L. Frison, F. De Marchi, M. Krampera, G. Semenzato, R. Fanin, A. Ambrosetti, M. Tiribelli.
Haematologica. 2015;100(8):e299–e301.
In vivo effects of mesenchymal stromal cells in two patients with severe acute respiratory distress syndrome
O.E. Simonson, D. Mougiakakos, N. Heldring, G. Bassi, H.J. Johansson, R. Jitschin, M. Dalén, S. Rodin, M. Corbascio, S. EL Andaloussi, O. PB Wiklander, J.Z. Nordin, J. Skog, C. Romain, T. Koestler, L. Hellgren-Johansson, P. Schiller, P-O. Joachimsson, H. Hägglund, M. Mattsson, J. Lehtiö, O.R. Faridani, R. Sandberg, O. Korsgren, M. Krampera, D.J. Weiss, K-H. Grinnemo, K. Le Blanc.
Stem Cells Transl Med. 2016;5(6):845.
Meninges harbor cells expressing neural precursor markers during development and adulthood
F. Bifari, V. Berton, A. Pino, M. Kusalo, G. Malpeli, M. Di Chio, E. Bersan, E. Amato, A. Scarpa, M. Krampera, G. Fumagalli, I. Decimo.
Front Cell Neurosci. 2015;9:383.
International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials
Galipeau J, Krampera M, Barrett J, Dazzi F, Deans RJ, DeBruijn J, Dominici M, Fibbe WE, Gee AP, Gimble JM, Hematti P, Koh MB, LeBlanc K, Martin I, McNiece IK, Mendicino M, Oh S, Ortiz L, Phinney DG, Planat V, Shi Y, Stroncek DF, Viswanathan S, Weiss DJ, Sensebe L.
Cytotherapy. 2016;18(2):151–159.
Notch signaling drives bone marrow stromal cell-mediated chemoresistance in acute myeloid leukemia
P.K. Takam, G. Bassi, A. Cassaro, M. Midolo, M. Di Trapani, F. Canella, R. Carusone, A. Gatti, F. Resci, O. Perbellini, M. Gottardi, M. Bonifacio, A.H. Nwabo Kamdje, A. Ambrosetti, M. Krampera.
Oncotarget. 2016;7(16):21713–21727.
Differential and transferable modulatory effects of mesenchymal stromal cell-derived extracellular vesicles on T, B and NK cell functions
M. Di Trapani, G. Bassi, M. Midolo, A. Gatti, P. Takam, A. Cassaro, R. Carusone, A. Adamo, M. Krampera.
Scientific Reports 2016;6:24120.
Identification of microRNAs implicated in the late differentiation stages of normal B cells suggest a central role for miRNA targets ZEB1 and TP53
G. Malpeli, S. Barbi, S. Zupo, G. Tosadori, G. Scardoni, A. Bertolaso, S. Sartoris, S. Ugel, A. Adamo, M. Krampera, M.T. Scupoli, C.M. Croce, A. Scarpa.
Oncotarget. 2017;8(7):11809–11826.
A relativity concept in mesenchymal stromal cell manufacturing
I. Martin, J. De Boer, L. Sensebe; MSC Committee of the International Society for Cellular Therapy (Collaborators: J. Galipeau, M. Krampera, D. Phinney, Y. Shi, A. Wixmerten).
Cytotherapy. 2016;18(5):613–620.
Mesenchymal stromal cells (MSCs) induce ex vivo proliferation and erythroid commitment of cord blood haematopoietic stem cells (CB-CD34+ cells)
Perucca S, Di Palma A, Piccaluga PP, Gemelli C, Zoratti E, Bassi G, Giacopuzzi E, Lojacono A, Borsani G, Tagliafico E, Scupoli MT, Bernardi S, Zanaglio C, Cattina F, Cancelli V, Malagola M, Krampera M, Marini M, Almici C, Ferrari S, Russo D.
PLoS One. 2017;12(2):e0172430.
Developmental pathways associated with cancer metastasis: Notch, Wnt, and Hedgehog
Nwabo Kamdje AH, Takam Kamga P, Tagne Simo R, Vecchio L, Seke Etet PF, Muller JM, Bassi G, Lukong E, Kumar Goel R, Mbo Amvene J, Krampera M.
Cancer Biol Med. 2017;14(2):109–120.
Mesenchymal stromal cells' role in tumor microenvironment: involvement of signaling pathways
Nwabo Kamdje AH, Kamga PT, Simo RT, Vecchio L, Seke Etet PF, Muller JM, Bassi G, Lukong E, Goel RK, Amvene JM, Krampera M.C.
Cancer Biol Med. 2017;14(2):129–141.
A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type gamma in chronic myeloid leukemia patients
Vezzalini M, Mafficini A, Tomasello L, Lorenzetto E, Moratti E, Fiorini Z, Holyoake TL, Pellicano F, Krampera M, Tecchio C, Yassin M, Al-Dewik N, Ismail MA, Al Sayab A, Monne M, Sorio C.
J Hematol Oncol. 2017;10(1):129.
Stem cells to restore insulin production and cure diabetes
Sordi V, Pellegrini S, Krampera M, Marchetti P, Pessina A, Ciardelli G, Fadini G, Pintus C, Pantè G, Piemonti L.
Nutr Metab Cardiovasc Dis. 2017;27(7):583–600.
Effective control of acute myeloid leukaemia and acute lymphoblastic leukaemia progression by telomerase specific adoptive T-cell therapy
Sandri S, De Sanctis F, Lamolinara A, Boschi F, Poffe O, Trovato R, Fiore A, Sartori S, Sbarbati A, Bondanza A, Cesaro S, Krampera M, Scupoli MT, Nishimura MI, Iezzi M, Sartoris S, Bronte V, Ugel S.
Oncotarget. 2017;8(50):86987–87001.
Adipocytes sustain pancreatic cancer progression through a noncanonical WNT paracrine network inducing ROR2 nuclear shuttling
Carbone C, Piro G, Gaianigo N, Ligorio F, Santoro R, Merz V, Simionato F, Zecchetto C, Falco G, Conti G, Kamga PT, Krampera M, Di Nicolantonio F, De Franceschi L, Scarpa A, Tortora G, Melisi D.
Int J Obes (Lond). 2018;42(3):334–343.
MicroRNA signatures and Foxp3+ cell count correlate with relapse occurrence in follicular lymphoma
Malpeli G, Barbi S, Greco C, Zupo S, Bertolaso A, Scupoli MT, Krampera M, Takam Kamga P, Croce C, Scarpa A, Zamò A.
Oncotarget. 2018;9(28):19961–19979.
Characterization of a new B-ALL cell line with constitutional defect of the Notch signaling pathway
Takam Kamga P, Dal Collo G, Bassi G, Midolo M, Delledonne M, Chilosi M, Bonifacio M, Krampera M.
Oncotarget. 2018;9(26):18341–18350.
Inhibition of Notch signaling enhances chemosensitivity in B-cell precursor acute lymphoblastic leukemia
Takam Kamga P, Dal Collo G, Midolo M, Adamo A, Delfino P, Mercuri A, Cesaro S, Mimiola E, Bonifacio M, Andreini A, Chilosi M, Krampera M.
Cancer Res. 2019;79(3):639–649.
Role of mesenchymal stromal cells-derived extracellular vescicles in tumour microenvironment
Adamo A, Dal Collo G, Bazzoni R, Krampera M.
Biochim Biophys Acta Rev Cancer. 2019;1871(1):192–198.
Extracellular vescicles mediate mesenchymal stromal cell-dependent regulation of B cell PI3K-AKT signaling pathway and actin cytoskeleton
Adamo A, Brandi J, Caligola S, Delfino P, Bazzoni R, Carusone R, Cecconi D, Giugno R, Manfredi M, Robotti E, Marengo E, Bassi G, Takam Kamga P, Dal Collo G, Gatti A, Mercuri A, Arigoni M, Olivero M, Calogero RA, Krampera M.
Front Immunol. 2019;10:446.
Is platelet gel safe enough for neutropenic patients?
Piccin A, Bacigalupo A, Zini G, Hamidieh AA, Bianchi M, Sica S, Valentini CG, Wolf D, Dazzi F, Fontanella F, Krampera M, Field S, Smith OP.
Transfus Apher Sci. 2019;58(2):190–191.
Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT) mesenchymal stromal cell committee position statement on nomenclature
Viswanathan S, shi Y, Galipeau J, Krampera M, Lebalnc K, Martin I, Nolta J, Phinney DG, Sensebe L.
Cytotherapy. 2019;21(10):1019–1024.
Notch signaling molecules as prognostic biomarkers for acute myeloid leukemia
Takam Kamga P, Dal Collo G, Resci F, Bazzoni R, Mercuri A, Quaglia FM, Tanasi I, Delfino P, Visco C, Bonifacio M, Krampera M.
Cancers (Basel). 2019;11(12):1958.
Functional dosing of mesenchymal stromal cell-derived extracellular vescicles for the prevention of acute graft-versus-host-disease
Dal Collo G, Adamo A, Gatti A, Tamellini E, Bazzoni R, Takam Kamga P, Tecchio C, Quaglia FM, Krampera M.
Stem Cells. 2020;10.1002/stem.3160
Regulative Loop between B-catenin and Protein Tyrosine Receptor Type gamma in Chronic Myeloid Leukemia
Tomasello L, Vezzalini M, Boni C, Bonifacio M, Scaffidi L, Yassin M, Al-Dewik N, Takam Kamga P, Krampera M, Sorio C.
Int J Mol Sci. 2020 Mar 26;21(7):2298.
Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential
Khoury M, Rocco PRM, Phinney DG, Krampera M, Martin I, Viswanathan S, Nolta JA, LeBlanc K, Galipeau J, Weiss DJ.
Cytotherapy. 2020 Nov;22(11):602-605
Small Molecule Inhibitors of Microenvironmental Wnt/B-Catenin Signaling Enhance the Chemosensitivity of Acute Myeloid Leukemia
Takam Kamga P, Dal Collo G, Cassaro A, Bazzoni R, Delfino P, Adamo A, Bonato A, Carbone C, Tanasi I, Bonifacio M, Krampera M.
Cancers (Basel). 2020 Sep 21;12(9):2696
High-throughput analysis and functional interpretation of extracellular vesicle content in hematological malignancies.
Tanasi I, Adamo A, Kamga PT, Bazzoni R, Krampera M.
Comput Struct Biotechnol J. 2020 Sep 24;18:2670-2677
Extracellular Vesicle-Dependent Communication Between Mesenchymal Stromal Cells and Immune Effector Cells.
Bazzoni R, Takam Kamga P, Tanasi I, Krampera M.
Front Cell Dev Biol. 2020 Nov 6;8:596079
HS-5 and HS-27A Stromal Cell Lines to Study Bone Marrow Mesenchymal Stromal Cell-Mediated Support to Cancer Development.
Adamo A, Delfino P, Gatti A, Bonato A, Takam Kamga P, Bazzoni R, Ugel S, Mercuri A, Caligola S, Krampera M.
Front Cell Dev Biol. 2020 Nov 5;8:584232
Emerging data supporting stromal cell therapeutic potential in cancer: reprogramming stromal cells of the tumor microenvironment for anti-cancer effects.
Kamdje AHN, Etet PFS, Simo RT, Vecchio L, Lukong KE, Krampera M.
Cancer Biol Med. 2020 Nov 15;17(4):828-841
The Evolving Knowledge on T and NK Cells in Classic Hodgkin Lymphoma: Insights into Novel Subsets Populating the Immune Microenvironment.
Ferrarini I, Rigo A, Visco C, Krampera M, Vinante F.
Cancers (Basel). 2020 Dec 14;12(12):E3757
Tumor Microenvironment Uses a Reversible Reprogramming of Mesenchymal Stromal Cells to Mediate Pro-tumorigenic Effects.
Nwabo Kamdje AH, Seke Etet PF, Simo Tagne R, Vecchio L, Lukong KE, Krampera M.
Front Cell Dev Biol. 2020 Nov 19;8:545126
The role of Notch and Wnt signaling in MSC communication in normal and leukemic bone marrow niche.
Takam Kamga P, Bazzoni R, Dal Collo G, Cassaro A, Tanasi I, Russignan A, Tecchio C, Krampera M.
Front Cell Dev Biol. 2021 Jan 8;8:599276
Targeting the Endothelin-1 receptors curtails tumor growth and angiogenesis in multiple myeloma.
Russignan A, Giada Dal Collo G, Bagnato AT, Tamassia N, Bugatti M, Belleri M, Lorenzi L, Borsi E, Bazzoni R, Gottardi M, Terragna C, Vermi W, Giacomini A, Presta M, Cassatella MA, Krampera M, Tecchio C.
Front Oncol. 2021 Jan 8;10:600025
Effects of CD20 antibodies and kinase inhibitors on B-cell receptor signalling and survival of chronic lymphocytic leukaemia cells.
Cavallini C, Galasso M, Pozza ED, Chignola R, Lovato O, Dando I, Romanelli MG, Krampera M, Pizzolo G, Donadelli M, Scupoli MT.
Br J Haematol. 2021 Jan;192(2):333-342
MSC variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition.
Galipeau J, Krampera M, Leblanc K, Nolta JA, Phinney DG, Shi Y, Tarte K, Viswanathan S, Martin I.
Cytotherapy. 2021 May;23(5):368-372
Interferon regulatory factor 7 impairs cellular metabolism in aging adipose-derived stromal cells.
Nodari A, Scambi I, Peroni D, Calabria E, Benati D, Mannucci S, Manfredi M, Frontini A, Visonà S, Bozzato A, Sbarbati A, Schena F, Marengo E, Krampera M, Galiè M.
J Cell Sci. 2021 Jun 1;134(11):jcs256230
Consensus International Council for Commonality in Blood Banking Automation-International Society for Cell & Gene Therapy statement on standard nomenclature abbreviations for the tissue of origin of mesenchymal stromal cells.
Viswanathan S, Ciccocioppo R, Galipeau J, Krampera M, Le Blanc K, Martin I, Moniz K, Nolta J, Phinney DG, Shi Y, Szczepiorkowski ZM, Tarte K, Weiss DJ, Ashford P.
Cytotherapy. 2021 Jun 8:S1465-3249(21)00644-7
Mesenchymal stromal cells: Putative microenvironmental modulators become cell therapy.
Krampera M, Le Blanc K.
Cell Stem Cell. 2021 Oct 7;28(10):1708-1725.doi: 10.1016/j.stem.2021.09.006
The transcriptional profile of adipose-derived stromal cells (ASC) mirrors the whitening of adipose tissue with age.
Scambi I, Peroni D, Nodari A, Merigo F, Benati D, Boschi F, Mannucci S, Frontini A, Visonà S, Sbarbati A, Krampera M, Galiè M.
Eur J Cell Biol. 2022 Feb 8;101(2):151206.
Update on the role and utility of extracellular vesicles in hematological malignancies.
Bazzoni R, Tanasi I, Turazzi N, Krampera M.
Stem Cells. 2022 Jul 27;40(7):619-629.
Successful preservation of native BCR-ABL1 in chronic myeloid leukemia primary leukocytes reveal a reduced kinase activity.
Boni C, Bonifacio M, Vezzalini M, Scaffidi L, Tomasello L, Parker LL, Boscarino D, Paladin D, Krampera M, Sorio C.
Front Oncol. 2022 Jun 8;12:904510.
An International Society for Cell and Gene Therapy Mesenchymal Stromal Cells Committee editorial on overcoming limitations in clinical trials of mesenchymal stromal cell therapy for coronavirus disease-19: time for a global registry.
Weiss DJ, Filiano A, Galipeau J, Khoury M, Krampera M, Lalu M, Blanc KL, Nolta J, Phinney DG, Rocco PRM, Shi Y, Tarte K, Viswanathan S, Martin I.
Cytotherapy. 2022 Aug 1:S1465-3249(22)00742-3.
The rs1001179 SNP and CpG methylation regulate catalase expression in chronic lymphocytic leukemia.
Galasso M, Dalla Pozza E, Chignola R, Gambino S, Cavallini C, Quaglia FM, Lovato O, Dando I, Malpeli G, Krampera M, Donadelli M, Romanelli MG, Scupoli MT.
Cellular and Molecular Life Sciences. 2022 Sep 16;79(10):521.
An International Society for Cell and Gene Therapy Mesenchymal Stromal Cells (MSC) Committee perspectives on International Standards Organization/Technical Committee 276 Biobanking Standards for bone marrow-MSCs and umbilical cord tissue-derived MSCs for research purposes.
Viswanathan S, Le Blanc K, Ciccocioppo R, Dagher G, Filiano A, Galipeau J, Krampera M, Krieger L, Lalu MM, Nolta J, Pardo VMR, Shi Y, Tarte K, Weiss DJ, Martin I.
Cytotherapy 2023 Aug;25(8):803-807.
Out of specification Tisagenlecleucel is associated with outcomes comparable to standard of care product in relapsed or refractory diffuse large B-cell lymphoma. Bone Marrow Transplant.
De Philippis C, Zucchinetti C, Mannina D, Krampera M, Zinzani PL, Chiappella A, di Rocco A, Orcioulo E, Tisi MC, Pistolese F, Giordano L, Santoro A, Bramanti S.
Bone Marrow Transplant. 2024 Apr;59(4):569-571.
Axicabtagene ciloleucel treatment is more effective in primary mediastinal large B-cell lymphomas than in diffuse large B-cell lymphomas: the Italian CART-SIE study.
Chiappella A, Casadei B, Chiusolo P, Di Rocco A, Ljevar S, Magni M, Angelillo P, Barbui AM, Cutini I, Dodero A, Bonifazi F, Tisi MC, Bramanti S, Musso M, Farina M, Martino M, Novo M, Grillo G, Patriarca F, Zacchi G, Krampera M, Pennisi M, Galli E, Martelli M, Ferreri AJM, Ferrari S, Saccardi R, Bermema A, Guidetti A, Miceli R, Zinzani PL, Corradini P.
Leukemia. 2024 May;38(5):1107-1114.
B-cell receptor signaling activity identifies patients with mantle cell lymphoma at higher risk of progression.
Gambino S, Quaglia FM, Galasso M, Cavallini C, Chignola R, Lovato O, Giacobazzi L, Caligola S, Adamo A, Putta S, Aparo A, Ferrarini I, Ugel S, Giugno R, Donadelli M, Dando I, Krampera M, Visco C, Scupoli MT.
Sci Rep. 2024 Mar 19;14(1):6595.
A rescue approach in refractory diffuse large B-cell lymphoma with obinutuzumab-redirected Cytokine-Induced Killer cells: a first-in-human case report.
Elice F, Sommaggio R, Cappuzzello E, Riva M, Tisi MC, Bernardi M, Bozza A, Catanzaro D, Chieregato K, Giaretta I, Dalla Pietà A, Krampera M, Merlo A, Trentin L, Visco C, Visentin A, Tosetto A, Astori G, Rosato A.
Haematologica. 2024 May 9. doi: 10.3324/haematol.2023.284881. Online ahead of print.
A multi-center real-life prospective study of axicabtagene ciloleucel versus tisagenlecleucel toxicity and outcomes in Large B-Cell Lymphomas.
Stella F, Chiappella A, Casadei B, Bramanti S, Ljevar S, Chiusolo P, Di Rocco A, Tisi MC, Carrabba MG, Cutini I, Martino M, Dodero A, Bonifazi F, Santoro A, Sora F, Botto B, Barbui AM, Russo D, Musso M, Grillo G, Krampera M, Olivieri J, Ladetto M, Cavallo F, Massaia M, Arcaini L, Pennisi M, Zinzani PL, Miceli R, Corradini P.
Blood Cancer Discov. 2024 Jul 2. doi: 10.1158/2643-3230.BCD-24-0052. Online ahead of print.